Title :
ModeRator - a software tool for comparison of stoichiometric models
Author :
Mednis, Martins ; Rove, Zintis ; Galvanauskas, Vytautas
Author_Institution :
Biosyst. Group, Latvia Univ. of Argiculture, Jelgava, Latvia
Abstract :
ModeRator is an online software tool for comparison of stoichiometric models written in COBRA-compatible format. Its main purpose is to detect the inconsistencies of complex models and to compare the models even without having Matlab and COBRA toolbox installed on a computer. The tool can be used online at http://biosystems.lv/moderator/ or hosted on a local computer. ModeRator is implemented in pure PHP, and its source code can be downloaded from http://sourceforge.net. The application and installation instructions are available. Additionally, a video tutorial is available on Youlube. ModeRator was tested on two representative genome-scale metabolic network models of Zymomonas Mobilis. The results show that the proposed software tool is able to correctly analyse/compare the models.
Keywords :
Internet; biochemistry; biology computing; interactive video; program testing; software tools; COBRA-compatible format; ModeRator testing; PHP implementation; YouTube; Zymomonas Mobilis; complex model inconsistency detection; constraints based reconstruction and analysis; genome-scale metabolic network models; installation instructions; online software tool; source code; stoichiometric models; video tutorial; Bioinformatics; Biological system modeling; Computational modeling; Genomics; MATLAB; Mathematical model; Robustness;
Conference_Titel :
Applied Computational Intelligence and Informatics (SACI), 2012 7th IEEE International Symposium on
Conference_Location :
Timisoara
Print_ISBN :
978-1-4673-1013-0
Electronic_ISBN :
978-1-4673-1012-3
DOI :
10.1109/SACI.2012.6249983
