Title :
Novel Quantum Dots for Enhanced Tumor Imaging
Author :
Nair, Ashwin ; Shen, Jinhui ; Thevenot, Paul ; Cai, Tong ; Hu, Zhibing ; Tang, Liping
Author_Institution :
Dept. of Bioeng., Univ. of Texas at Arlington, Arlington, TX
Abstract :
So as to develop an effective tool for tumor imaging, we have embedded quantum dots (QD) in hydrogel nanoparticles. Their uptake in cancer cells has been studied in vitro and in a mice tumor model. Compared with QD alone, the QDs embedded in nanoparticles showed higher uptake in the tumor tissue. This novel conjugate can serve as a good imaging tool and also has the potential to serve as a carrier for drugs.
Keywords :
biomedical optical imaging; cancer; gels; nanobiotechnology; nanoparticles; semiconductor quantum dots; tumours; cancer cells; drug carrier; embedded quantum dots; enhanced tumor imaging; hydrogel nanoparticles; imaging tool; quantum dots; tumor tissue; Cancer; Drugs; Fluorescence; In vitro; In vivo; Mice; Microscopy; Nanoparticles; Neoplasms; Quantum dots;
Conference_Titel :
Nanotechnology, 2008. NANO '08. 8th IEEE Conference on
Conference_Location :
Arlington, Texas
Print_ISBN :
978-1-4244-2103-9
Electronic_ISBN :
978-1-4244-2104-6
DOI :
10.1109/NANO.2008.197
