Title :
Terahertz Spectroscopy of Furosemide
Author :
Min, Ge ; Zhaoxia, Zhang ; Hongwei, Zhao ; Wenxin, Li ; Wenfeng, Wang
Author_Institution :
Chinese Acad. of Sci., Shanghai
Abstract :
Low frequency vibrational modes of furosemide were measured with terahertz time domain spectroscopy at room temperature. The different crystalline forms of furosemide were also measured. A clear difference between their spectra was observed. This makes the identification of polymorphs of furosemide easy and quick.
Keywords :
absorption coefficients; drugs; pharmaceutical technology; submillimetre wave spectra; submillimetre wave spectroscopy; vibrational modes; absorption coefficients; crystalline forms; drug polymorphs; frequency 0.2 THz to 1.7 THz; furosemide polymorphs; low frequency vibrational modes; pharmaceutical industry; temperature 293 K to 298 K; terahertz time domain spectroscopy; Crystallization; Discrete Fourier transforms; Drugs; Frequency; Material properties; Powders; Spectroscopy; Temperature; Vibration measurement; X-ray scattering;
Conference_Titel :
Infrared Millimeter Waves and 14th International Conference on Teraherz Electronics, 2006. IRMMW-THz 2006. Joint 31st International Conference on
Conference_Location :
Shanghai
Print_ISBN :
1-4244-0400-2
Electronic_ISBN :
1-4244-0400-2
DOI :
10.1109/ICIMW.2006.368688
