Flexible neural probes with micro-fluidic channels for stable interface with the nervous system

Author

Suzuki, T. ; Ziegler, D. ; Mabuchi, K. ; Takeuchi, S.

Author_Institution

Graduate Sch. of Inf. Sci. & Technol., Tokyo Univ., Japan

Volume

2

fYear

2004

fDate

1-5 Sept. 2004

Firstpage

4057

Lastpage

4058

Abstract

A flexible neural probe with micro-fluidic channels has been developed. The probe is sufficiently flexible to enable minimally invasive recording. The fluidic channel integrated on the probe is capable of injecting chemicals into neural tissues. In addition, it permits a stable interface with the nervous system. We focus on issues concerning: 1) stable recording with electrodes placed in fluidic channels, 2) improved mechanical stiffness by filling channels with a solid that dissolves in neural tissues, and 3) the probe´s application to a nerve regeneration electrode.

Keywords

biological tissues; biomedical electrodes; microfluidics; neurophysiology; chemical injection; flexible neural probes; improved mechanical stiffness; microfluidic channels; minimally invasive recording; nerve regeneration electrode; nervous system; neural tissues; stable recording; Biological materials; Control systems; Electrodes; Fabrication; Humans; Microfluidics; Nervous system; Neural prosthesis; Probes; Silicon; BMI; Parylene; flexible neural probe; micro-fluidic channel; nerve regeneration electrode;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE

Conference_Location

San Francisco, CA

Print_ISBN

0-7803-8439-3

Type

conf

DOI

10.1109/IEMBS.2004.1404132

Filename

1404132