DocumentCode
2744137
Title
THz Time-Domain Spectroscopy of Thin-Film DNA Oligomer Having Mismatch
Author
Norizawa, Kimihiro ; Tabata, Hitoshi ; Takei, Fumie ; Nakatani, Kazuhiko
Author_Institution
Osaka Univ., Osaka
fYear
2006
fDate
18-22 Sept. 2006
Firstpage
579
Lastpage
579
Abstract
THz spectroscopy and imaging is useful for hybridization assessment compared with conventional methods using fluorescence indicators, because THz method can give the hybridization information without any indicators. We have successfully obtained the THz spectrum using 11mers having G-G mismatch and found a very clear peak structure in the spectrum. We also report the THz spectra of 11mers with naphthyridine dimmer binding to G-G mismatch.
Keywords
DNA; biological techniques; genetics; molecular biophysics; submillimetre wave imaging; submillimetre wave spectra; THz spectra; conventional fluorescence indicators; hybridization assessment; naphthyridine dimmer binding; terahertz imaging; terahertz time-domain spectroscopy; thin-film DNA oligomer; Biomedical equipment; DNA; Frequency; Glass; Medical services; Spectroscopy; Substrates; Temperature; Time domain analysis; Transistors;
fLanguage
English
Publisher
ieee
Conference_Titel
Infrared Millimeter Waves and 14th International Conference on Teraherz Electronics, 2006. IRMMW-THz 2006. Joint 31st International Conference on
Conference_Location
Shanghai
Print_ISBN
1-4244-0400-2
Electronic_ISBN
1-4244-0400-2
Type
conf
DOI
10.1109/ICIMW.2006.368786
Filename
4222520
Link To Document