Title :
Terahertz pulsed imaging and spectroscopy of breast tumours
Author :
Wallace, V.P. ; Pickwell, E. ; Fitzgerald, A.J. ; Pinder, S.
Author_Institution :
TeraView Ltd., Cambridge
Abstract :
We report on a study using TPI for imaging breast tumours ex vivo. Several breast samples were imaged and parameters from the time domain impulse functions were used to reveal contrast. Good correlation was found for area and shape of tumour in the THz images compared to that of histology. Terahertz spectroscopy shows that both the absorption coefficient and refractive index were higher for breast tissue containing tumor compared to normal. This study demonstrates the potential of TPI to image both invasive breast carcinomas and ductal carcinoma in situ using THz and encourages further studies.
Keywords :
absorption coefficients; biomedical optical imaging; cancer; refractive index; submillimetre wave imaging; submillimetre wave spectroscopy; tumours; absorption coefficient; breast tissue; breast tumours; ductal carcinoma; invasive breast carcinomas; refractive index; terahertz pulsed imaging; terahertz spectroscopy; Absorption; Breast neoplasms; Breast tissue; Breast tumors; Frequency dependence; Humans; Optical imaging; Optical pulses; Refractive index; Spectroscopy;
Conference_Titel :
Infrared Millimeter Waves and 14th International Conference on Teraherz Electronics, 2006. IRMMW-THz 2006. Joint 31st International Conference on
Conference_Location :
Shanghai
Print_ISBN :
1-4244-0399-5
Electronic_ISBN :
1-4244-0400-2
DOI :
10.1109/ICIMW.2006.368792