EEG-MEG source characterization in post surgical epilepsy: the influence of large cerebrospinal fluid compartments

Author

Huiskamp, Geertjan

Author_Institution

Dept. of Clinical Neurophysiology, University Medical Center, Utrecht, Netherlands

Volume

2

fYear

2004

fDate

1-5 Sept. 2004

Firstpage

4401

Lastpage

4404

Abstract

A study on the effect of including a large post-surgical cavity filled with cerebrospinal fluid (CSF) in the modeling of EEG-MEG in epilepsy was performed. Real, simultaneous EEG-MEG data and volume conductor models constructed on the basis of 3DT1 MRI data of the same patient were used. Results show that for MEG and EEG source localization errors remain limited to 0.5 cm, but source strengths found are more consistent when CSF is included. Also the localization differences between EEG and MEG are smaller and the fit to MEG data is substantially better.

Keywords

biomedical MRI; diseases; electroencephalography; magnetoencephalography; medical signal processing; surgery; 3DT1 MRI; EEG-MEG source localization; large cerebrospinal fluid compartments; post surgical epilepsy; volume conductor models; Brain modeling; Conductivity; Conductors; Current distribution; Electroencephalography; Epilepsy; Medical treatment; Skin; Skull; Surgery; EEG; MEG; epilepsy;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE

Conference_Location

San Francisco, CA

Print_ISBN

0-7803-8439-3

Type

conf

DOI

10.1109/IEMBS.2004.1404224

Filename

1404224