• DocumentCode
    2750430
  • Title

    Non-invasive assessment of tumor proliferation using triple quantum filtered 23Na MRI: technical challenges and solutions

  • Author

    Boada, F.E. ; Tanase, C. ; Davis, D. ; Walter, K. ; Torres-Trejo, A. ; Couce, M. ; Hamilton, R. ; Kondziolka, D. ; Bartynski, W. ; Lieberman, F.

  • Author_Institution
    Pittsburgh Univ., PA, USA
  • Volume
    2
  • fYear
    2004
  • fDate
    1-5 Sept. 2004
  • Firstpage
    5238
  • Lastpage
    5241
  • Abstract
    We address the development of triple-quantum-filtered sodium MRI as a non-invasive surrogate measure for cell proliferation in brain tumors. We demonstrate that through careful consideration of the theoretical description of the signal, triple-quantum-filtered sodium images of adequate signal-to-noise ratio (SNR) can be acquired in clinically acceptable imaging times.
  • Keywords
    biomedical MRI; brain; cancer; cellular biophysics; medical image processing; tumours; Na; brain tumors; cell proliferation; technical challenges; triple quantum filtered /sup 23/Na MRI; tumor proliferation; Biopsy; Electric breakdown; In vivo; Magnetic resonance imaging; Neoplasms; Nuclear magnetic resonance; Nuclear measurements; Optical imaging; Optical microscopy; Signal to noise ratio;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
  • Conference_Location
    San Francisco, CA
  • Print_ISBN
    0-7803-8439-3
  • Type

    conf

  • DOI
    10.1109/IEMBS.2004.1404464
  • Filename
    1404464