Title :
Computer modeling of active center of hemorphins
Author :
Akverdieva, G.A. ; Nabiyev, A.M. ; Godjayev, N.M.
Author_Institution :
Inst. for Phys. Problems, Baku State Univ., Baku, Azerbaijan
Abstract :
The molecular dynamics of hemorphin-4 peptide, corresponding to the sequence of the physiologically active center Tyr-Pro-Trp-Thr of hemorphins, was investigated. Simulations were carried out for stabile conformational states of this tetrapeptide in 7 ns time interval using computer modeling program. On the base obtained results the aminoacids side chains flexibility were analysed.
Keywords :
molecular biophysics; molecular configurations; molecular dynamics method; organic compounds; physiological models; active center; aminoacid side chain flexibility; computer modeling proqram; conformational states; hemorphin-4 peptide; molecular dynamics simulation; physiologically active center Tyr-Pro-Trp-Thr; tetrapeptide; time 7 ns; Biological system modeling; Computational modeling; Computers; Educational institutions; Immune system; Peptides; Roads; conformation; hemorphin; molecular dynamics simulations;
Conference_Titel :
Application of Information and Communication Technologies (AICT), 2011 5th International Conference on
Conference_Location :
Baku
Print_ISBN :
978-1-61284-831-0
DOI :
10.1109/ICAICT.2011.6111016
