Modeling Biological Pathways: An Object-Oriented like Methodology Based on Mean Field Analysis

Author

Francesca, Cordero ; Daniele, Manini ; Marco, Gribaudo

Author_Institution

Dept. of Clinical & Biol. Sci., Univ. of Torino, Turin, Italy

fYear

2009

fDate

11-16 Oct. 2009

Firstpage

117

Lastpage

122

Abstract

In this paper we propose an object-oriented methodology based on mean field analysis that can be used to describe in an intuitive manner the behavior of systems composed by a large number of interacting objects. For instance, this technique is well suited to study complex biopathways. We apply this approach to model the lac operon gene regulatory mechanism and glycolysis pathway. Numerical results obtained from the analysis of the model are presented.

Keywords

biology computing; genetics; object-oriented programming; biological pathways; complex biopathways; glycolysis pathway; lac operon gene regulatory mechanism; mean field analysis; object-oriented like methodology; Application software; Biological system modeling; Biological systems; Biology computing; Character generation; Computer applications; Computer science; Object oriented modeling; Switches; Systems biology; Biological Pathways; Mean Field Analysis;

fLanguage

English

Publisher

ieee

Conference_Titel

Advanced Engineering Computing and Applications in Sciences, 2009. ADVCOMP '09. Third International Conference on

Conference_Location

Sliema

Print_ISBN

978-1-4244-5082-4

Electronic_ISBN

978-0-7695-3829-7

Type

conf

DOI

10.1109/ADVCOMP.2009.25

Filename

5359563