Towards Precise Simulation of Optical Elastography Technique

Optical elastography is a promising new imaging technique which utilizes optical frequency radiation to produce images of elastic modulus distribution of compliant tissue. Elastography practice is generally accomplished under the assumption of a linear stress-strain relationship in biological tissue. This assumption is not valid for most biological tissues even for small applied compressions. The nonlinear stress-strain relationship of different tissue types significantly impacts on the contrast in elastography images; so it is crucial to consider this characteristic in order to achieve a more realistic simulation of this technique. In this paper, we represent the achieved analytic expression predicting the Young modulus alterations of a soft biological tissue due to applied force in terms of some tissuepsilas specifications, with consideration of elastography procedure and in the case of nonlinear stress-strain relationship which is valid for most soft tissues. This model is achieved base on analytic solution of 2D elasticity problem for a circular homogeneous inclusion attached to a homogeneous infinite medium in the case of a plane-strain state.