Title :
A cDNA microarray for rapid and economical identification of HLA profiles of individuals
Author :
Zhang, Guang Lan ; Keskin, Derin B. ; Reinherz, Ellis L. ; Brusic, Vladimir
Author_Institution :
Cancer Vaccine Center, Dana-Farber Cancer Inst., Boston, MA, USA
Abstract :
High resolution HLA typing is essential for matching donors and recipients for blood and marrow transplantation and helps with the diagnosis of HLA-associated diseases. We developed HLA microarray and related software for rapid and accurate high resolution HLA genotyping.
Keywords :
DNA; blood; cellular biophysics; lab-on-a-chip; medical diagnostic computing; molecular biophysics; proteins; blood; cDNA microarray; disease diagnosis; economical identification; high-resolution genotyping; human leukocyte antigens genes; marrow transplantation; matching donors; microarray; software; Algorithm design and analysis; Arrays; Cancer; Probes; Signal processing algorithms; USA Councils; Vaccines; HLA genotyping; HLA profiling; cDNA tiling microarray;
Conference_Titel :
Bioinformatics and Biomedicine Workshops (BIBMW), 2011 IEEE International Conference on
Conference_Location :
Atlanta, GA
Print_ISBN :
978-1-4577-1612-6
DOI :
10.1109/BIBMW.2011.6112451
