Title :
Joint analysis of host and pathogen genomes
Author :
Bartha, István ; Telenti, Amalio ; Müller, Viktor ; Fellay, Jacques
Author_Institution :
Inst. of Microbiol., Univ. of Lausanne, Lausanne, Switzerland
Abstract :
Joint analysis of existing host genetic and HIV sequencing data has been limited so far to HLA alleles and viral mutations. We performed a genome-wide survey of associations between human single nucletide polymorphisms (SNP) and HIV genetic variation across the whole viral genome.
Keywords :
cellular biophysics; genetics; genomics; microorganisms; polymorphism; HIV genetic variation; HIV sequencing data; HLA alleles; genome-wide survey; host genetic; human single nucletide polymorphism; pathogen genomes; viral genome; viral mutation; Bioinformatics; Conferences; Genomics; Human immunodeficiency virus; Humans; Logistics; GWAS; HIV; phylogenetics;
Conference_Titel :
Bioinformatics and Biomedicine Workshops (BIBMW), 2011 IEEE International Conference on
Conference_Location :
Atlanta, GA
Print_ISBN :
978-1-4577-1612-6
DOI :
10.1109/BIBMW.2011.6112509