Feedback Neurocontrol of a Disease

We consider a simple mathematical model of a disease. It includes four coupled nonlinear equations and four state variables for pathogens, plasma cells, antibodies and patient health indicator. Depending on initial values of state variables (concentrations) and without control, the model exhibits at least four possible classes of behavior. We treat the system of equations from the standpoint of feedback neurocontrol. We show that various feedback control strategies (due to injection of therapeutic agents) are possible and effective. We also discuss ways of making the "patient controller" more robust with respect to realistic uncertainties.