• DocumentCode
    2773067
  • Title

    Solving MEC and MEC/GI Problem Models, Using Information Fusion and Multiple Classifiers

  • Author

    Asgarian, Ehsan ; Moeinzadeh, M-Hossein ; Mohammadzadeh, Javad ; Ghazinezhad, Ali ; Habibi, Jafar ; Najafi-Ardabili, Amir

  • Author_Institution
    Sharif Univ. of Technol., Tehran
  • fYear
    2007
  • fDate
    18-20 Nov. 2007
  • Firstpage
    397
  • Lastpage
    401
  • Abstract
    Mutations in single nucleotide polymorphisms (SNPs - different variant positions (1%) from human genomes) are responsible for some genetic diseases. As a consequence, obtaining all SNPs from human populations is one of the primary goals of recent studies in human genomics. Two sequences of mentioned SNPs in diploid human organisms are called haplotypes. In this paper, we study haplotype reconstruction from SNP-fragments with and without genotype information, problems. Designing serial and parallel classifiers was center of our research. Genetic algorithm and K-means were two components of our approaches. This combination helps us to cover the single classifier´s weaknesses.
  • Keywords
    biology computing; genetic algorithms; genetics; pattern classification; sensor fusion; MEC/GI problem models; genetic algorithm; genetic diseases; haplotype reconstruction; human genomes; information fusion; k-means algorithm; multiple classifiers; parallel classifiers; serial classifiers; single nucleotide polymorphisms; Bioinformatics; Classification algorithms; Databases; Error analysis; Genomics; Humans; Java; Mathematical model; Mathematics; Statistics; Multiple Classifier Systems; Parallel classifiers; SNP fragments; Serial classifiers; classification; genotype information; haplotype; reconstruction rate;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Innovations in Information Technology, 2007. IIT '07. 4th International Conference on
  • Conference_Location
    Dubai
  • Print_ISBN
    978-1-4244-1840-4
  • Electronic_ISBN
    978-1-4244-1841-1
  • Type

    conf

  • DOI
    10.1109/IIT.2007.4430390
  • Filename
    4430390