DocumentCode
2773067
Title
Solving MEC and MEC/GI Problem Models, Using Information Fusion and Multiple Classifiers
Author
Asgarian, Ehsan ; Moeinzadeh, M-Hossein ; Mohammadzadeh, Javad ; Ghazinezhad, Ali ; Habibi, Jafar ; Najafi-Ardabili, Amir
Author_Institution
Sharif Univ. of Technol., Tehran
fYear
2007
fDate
18-20 Nov. 2007
Firstpage
397
Lastpage
401
Abstract
Mutations in single nucleotide polymorphisms (SNPs - different variant positions (1%) from human genomes) are responsible for some genetic diseases. As a consequence, obtaining all SNPs from human populations is one of the primary goals of recent studies in human genomics. Two sequences of mentioned SNPs in diploid human organisms are called haplotypes. In this paper, we study haplotype reconstruction from SNP-fragments with and without genotype information, problems. Designing serial and parallel classifiers was center of our research. Genetic algorithm and K-means were two components of our approaches. This combination helps us to cover the single classifier´s weaknesses.
Keywords
biology computing; genetic algorithms; genetics; pattern classification; sensor fusion; MEC/GI problem models; genetic algorithm; genetic diseases; haplotype reconstruction; human genomes; information fusion; k-means algorithm; multiple classifiers; parallel classifiers; serial classifiers; single nucleotide polymorphisms; Bioinformatics; Classification algorithms; Databases; Error analysis; Genomics; Humans; Java; Mathematical model; Mathematics; Statistics; Multiple Classifier Systems; Parallel classifiers; SNP fragments; Serial classifiers; classification; genotype information; haplotype; reconstruction rate;
fLanguage
English
Publisher
ieee
Conference_Titel
Innovations in Information Technology, 2007. IIT '07. 4th International Conference on
Conference_Location
Dubai
Print_ISBN
978-1-4244-1840-4
Electronic_ISBN
978-1-4244-1841-1
Type
conf
DOI
10.1109/IIT.2007.4430390
Filename
4430390
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