DocumentCode :
2780921
Title :
Frequency domain hammerstein model of glucose-insulin process in IDDM patient
Author :
Bhattacharjee, Arpita ; Sutradhar, Ashoke
Author_Institution :
Dept. of Electr. Eng., Bengal Eng. & Sci. Univ., Howrah, India
fYear :
2010
fDate :
16-18 Dec. 2010
Firstpage :
132
Lastpage :
137
Abstract :
This paper deals with a frequency domain kernel estimation problem for modeling a nonlinear dynamic system of multivariable glucose-insulin process in an insulin dependent diabetes mellitus (IDDM) patient. For such a process with uncertainties and parameter variations, the nonparametric models are most useful for closed loop model predictive control. The present work proposes a frequency domain kernel estimation of a Hammerstein model using the harmonic excitation input by taking FFT on the input data sequence from the glucose-insulin process of IDDM patient model. For the multivariable system, the first block is a two-input single output nonlinear block followed by a SISO linear filter. The adaptive recursive least square (ARLS) algorithm is used to solve up to second order kernels of Volterra equations with extended input vector consisting of self and cross components. Twice the length of the extended input vector for the MISO system was considered for finding the kernels and the output in frequency domain. The input-output data taken from the first principle model of nonlinear process, have been used to identify the system with a short filter memory length of M=2 and the validation results have shown good fit both in frequency and time domain responses.
Keywords :
ab initio calculations; diseases; drug delivery systems; fast Fourier transforms; filters; physiological models; sugar; FFT; IDDM patient model; MISO system; SISO linear filter; Volterra equations; adaptive recursive least square algorithm; closed loop model predictive control; data sequence; drug delivery system; first principle model; frequency domain Hammerstein model; frequency domain kernel estimation problem; frequency domain response; harmonic excitation input; insulin dependent diabetes mellitus patient; multivariable glucose-insulin process; nonlinear dynamic system; nonparametric models; short filter memory length; time domain response; two-input single output nonlinear block; Frequency domain analysis; Insulin; Kernel; Mathematical model; Nonlinear dynamical systems; Sugar; Time domain analysis; Hammerstein model; System identification; frequency domain kernels; glucose-insulin interaction; nonparametric model;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Systems in Medicine and Biology (ICSMB), 2010 International Conference on
Conference_Location :
Kharagpur
Print_ISBN :
978-1-61284-039-0
Type :
conf
DOI :
10.1109/ICSMB.2010.5735359
Filename :
5735359
Link To Document :
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