• DocumentCode
    2780921
  • Title

    Frequency domain hammerstein model of glucose-insulin process in IDDM patient

  • Author

    Bhattacharjee, Arpita ; Sutradhar, Ashoke

  • Author_Institution
    Dept. of Electr. Eng., Bengal Eng. & Sci. Univ., Howrah, India
  • fYear
    2010
  • fDate
    16-18 Dec. 2010
  • Firstpage
    132
  • Lastpage
    137
  • Abstract
    This paper deals with a frequency domain kernel estimation problem for modeling a nonlinear dynamic system of multivariable glucose-insulin process in an insulin dependent diabetes mellitus (IDDM) patient. For such a process with uncertainties and parameter variations, the nonparametric models are most useful for closed loop model predictive control. The present work proposes a frequency domain kernel estimation of a Hammerstein model using the harmonic excitation input by taking FFT on the input data sequence from the glucose-insulin process of IDDM patient model. For the multivariable system, the first block is a two-input single output nonlinear block followed by a SISO linear filter. The adaptive recursive least square (ARLS) algorithm is used to solve up to second order kernels of Volterra equations with extended input vector consisting of self and cross components. Twice the length of the extended input vector for the MISO system was considered for finding the kernels and the output in frequency domain. The input-output data taken from the first principle model of nonlinear process, have been used to identify the system with a short filter memory length of M=2 and the validation results have shown good fit both in frequency and time domain responses.
  • Keywords
    ab initio calculations; diseases; drug delivery systems; fast Fourier transforms; filters; physiological models; sugar; FFT; IDDM patient model; MISO system; SISO linear filter; Volterra equations; adaptive recursive least square algorithm; closed loop model predictive control; data sequence; drug delivery system; first principle model; frequency domain Hammerstein model; frequency domain kernel estimation problem; frequency domain response; harmonic excitation input; insulin dependent diabetes mellitus patient; multivariable glucose-insulin process; nonlinear dynamic system; nonparametric models; short filter memory length; time domain response; two-input single output nonlinear block; Frequency domain analysis; Insulin; Kernel; Mathematical model; Nonlinear dynamical systems; Sugar; Time domain analysis; Hammerstein model; System identification; frequency domain kernels; glucose-insulin interaction; nonparametric model;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Systems in Medicine and Biology (ICSMB), 2010 International Conference on
  • Conference_Location
    Kharagpur
  • Print_ISBN
    978-1-61284-039-0
  • Type

    conf

  • DOI
    10.1109/ICSMB.2010.5735359
  • Filename
    5735359