Title :
A numerical fitting technique for quantitative magnetic resonance spectroscopy [clinical NMR]
Author :
Webb, S. ; Leach, M.O. ; Collins, D.J. ; Bentley, R.E.
Author_Institution :
Joint Dept. of Phys., Inst. of Cancer Res., R. Marsden Hospital, Sutton, UK
Abstract :
A new numerical fitting technique has been developed based on the optimisation strategy known as `simulated annealing´. This builds a fit to the measured spectrum in such a way that the magnitude of the separate spectral components is generated en passant by the fitting process. The starting point is to identify the centre frequencies from the measured spectrum. The numerical method consists of offering `grains of spectrum-spexels´ at random
Keywords :
biomedical NMR; biomedical measurement; curve fitting; nuclear magnetic resonance spectroscopy; simulated annealing; spectral analysis; biomedical NMR spectroscopy; centre frequencies; curve fitting; non-Lorentzian behaviour; numerical fitting technique; optimisation strategy; quantitative magnetic resonance; simulated annealing; spexels;
Conference_Titel :
Technical Developments Relating to Clinical NMR in the UK, IEE Colloquium on
Conference_Location :
London
