Multi-modal perceptualization of volumetric data and its application to molecular docking

Author

Maciejewski, Ross ; Choi, Seungmoon ; Ebert, David S. ; Tan, Hong Z.

Author_Institution

Sch. of Electr. & Comput. Eng., Purdue Univ., West Lafayette, IN, USA

fYear

2005

fDate

18-20 March 2005

Firstpage

511

Lastpage

514

Abstract

In this paper, we present a multi-modal data perceptualization system used to analyze the benefits of augmenting a volume docking problem with other perceptual cues, particularly stereoscopic vision and haptic rendering. This work focuses on the problem of matching complex three-dimensional shapes in order to reproduce known configurations. Specifically, we focus on the docking of two proteins, actin and cofilin, responsible for cellular locomotion. Users were shown examples of cofilin combining with actin and asked to reproduce this match. Accuracy of the match and completion time were measured and analyzed in order to quantify the benefits of augmenting tools for such a task.

Keywords

data visualisation; haptic interfaces; interactive systems; pattern matching; proteins; rendering (computer graphics); stereo image processing; visual perception; actin; cellular locomotion; cofilin; haptic rendering; molecular docking; multimodal volumetric data perceptualization system; proteins; stereoscopic vision; three-dimensional shape matching; volume docking problem; Computational modeling; Data visualization; Force feedback; Haptic interfaces; Packaging; Proteins; Rendering (computer graphics); Shape; Time measurement; Transfer functions;

fLanguage

English

Publisher

ieee

Conference_Titel

Eurohaptics Conference, 2005 and Symposium on Haptic Interfaces for Virtual Environment and Teleoperator Systems, 2005. World Haptics 2005. First Joint

Print_ISBN

0-7695-2310-2

Type

conf

DOI

10.1109/WHC.2005.97

Filename

1406988