Title :
Fluorescence detection system using a metal-coated glass micropipette
Author :
Shuzo, Masaki ; Okada, Koutaroh ; Kanzaki, Ryohei ; Shimoyama, Isao
Abstract :
We propose a probing system for measurement of chemical concentration from deep tissue. The detection region of the probe of 0.5 mum-diameter was 0.134 mum in depth by FDTD simulation. Using this probe, calcium fluorescence at gradual depth was measured from a deep area of an insect brain where it was difficult by the optical microscope.
Keywords :
biomedical electrodes; chemical variables measurement; finite difference time-domain analysis; microelectrodes; FDTD; chemical concentration measurement; deep tissue; fluorescence detection system; insect brain; metal-coated glass micropipette; size 0.5 mum to 0.134 mum; Area measurement; Brain modeling; Calcium; Chemicals; Finite difference methods; Fluorescence; Glass; Optical microscopy; Probes; Time domain analysis;
Conference_Titel :
Micro Electro Mechanical Systems, 2007. MEMS. IEEE 20th International Conference on
Conference_Location :
Hyogo
Print_ISBN :
978-1-4244-095-5
Electronic_ISBN :
1084-6999
DOI :
10.1109/MEMSYS.2007.4433100
