DocumentCode
2800340
Title
A simple cellular automaton model for tumor-immunity system
Author
Hu, Rose ; Ruan, Xinbo
Author_Institution
Sch. of Electron. Inf. & Control Eng., Beijing Polytech. Univ., China
Volume
2
fYear
2003
fDate
8-13 Oct. 2003
Firstpage
1031
Abstract
This article builds a sort of immune system model basing on cellular automata method, in order to simulate the immune response to tumor growth. This paper discusses immune-tumor system at the cellular level, based on the simple two-dimensional stochastic discrete cellular automaton model. In this simple three-layer structure designers take into account the features of the immune response, and regard many different kinds of immune cells as the single immune element. The model describes the interaction between cancer and immune cells, and shows immune cells growth around tumor. The authors study the normal cellular automaton model, and design the evolution growth rules. At last we build discrete cellular automaton model of tumor-immune system, and simulate tumor-immune system on computer. The model predicts the dynamics of the tumor-immune system in agreement with Gompertz growth. Via adjusting different parameters of simulating model, the ultimate results indicate the basal behaviors of tumor-immune system exactly.
Keywords
cancer; cellular automata; cellular biophysics; physiological models; tumours; Gompertz growth; cancer; immune cells growth; immune element; immune response; three layer structure designers; tumor growth; tumor-immune system; tumor-immunity system; two dimensional stochastic discrete cellular automaton model; Automata; Biological system modeling; Cancer; Computational modeling; Evolution (biology); Immune system; Mathematical model; Neoplasms; Power system modeling; Predictive models;
fLanguage
English
Publisher
ieee
Conference_Titel
Robotics, Intelligent Systems and Signal Processing, 2003. Proceedings. 2003 IEEE International Conference on
Print_ISBN
0-7803-7925-X
Type
conf
DOI
10.1109/RISSP.2003.1285731
Filename
1285731
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