Flat-based controlled fed-batch fermentation of the bacterium Photorhabdus luminescens

Author

Seydel, Peter ; Röck, Helmut

Author_Institution

Fac. of Eng., Kiel Univ., Germany

fYear

2000

fDate

2000

Firstpage

38

Lastpage

43

Abstract

In this paper, a model based fed-batch strategy for the cultivation of the bacterium Photorhabdus luminescens is proposed. The development of an appropriate trajectory for bacterial growth and substrate feed rate can be obtained using the theory of flat systems introduced by Fliess et al. (1992). To avoid deviations from a desired trajectory caused by model uncertainties or disturbances, a nonlinear controller is presented allowing closed loop control of the fermentation process

Keywords

batch processing (industrial); biotechnology; closed loop systems; fermentation; microorganisms; nonlinear control systems; process control; stability; uncertain systems; bacterial growth; bacterium Photorhabdus luminescens; closed loop control; disturbances; flat-based controlled fed-batch fermentation; model uncertainties; nonlinear controller; substrate feed rate; Automatic control; Biological system modeling; Chemicals; Feeds; Insects; Mathematical model; Microorganisms; Nonlinear dynamical systems; Nonlinear systems; Symbiosis;

fLanguage

English

Publisher

ieee

Conference_Titel

Control Applications, 2000. Proceedings of the 2000 IEEE International Conference on

Conference_Location

Anchorage, AK

Print_ISBN

0-7803-6562-3

Type

conf

DOI

10.1109/CCA.2000.897396

Filename

897396