DocumentCode :
2805461
Title :
3D non-linear enhancement of tubular microscopic bone porosities
Author :
Pacureanu, Alexandra ; Larrue, Aymeric ; Peter, Zsolt ; Peyrin, Françoise
Author_Institution :
CREATIS-LRMN, Univ. de Lyon, Lyon, France
fYear :
2009
fDate :
June 28 2009-July 1 2009
Firstpage :
602
Lastpage :
605
Abstract :
The investigation of cellular aspects of bone tissue is generally performed from 2D microscopic techniques. Recent advances in Synchrotron Radiation Micro-CT allow to image biological samples at a sub-micrometric scale. In this paper, we propose to study the feasibility of this technique to study the bone lacuno-canalicular system, consisting in a complex network of thin canaliculi (diameter ~500 nm) joining osteocytes. Due to the limited spatial resolution of the imaging system compared to the structure size and the constraints in term of dose, the images have a low signal to noise ratio and the detection of canaliculi is challenging. We propose a 3D non-linear enhancement technique based on Hessian analysis. The method is first evaluated on synthetic images, then we show, for the first time, a 3D rendering of the canalicular network based on experimental data.
Keywords :
bone; computerised tomography; image enhancement; image resolution; medical image processing; 3D lacuno-canalicular system; 3D nonlinear enhancement; Hessian analysis; micro computed tomography; osteocytes; porosities; spatial resolution; thin canaliculi complex network; tubular microscopic bone; Bone diseases; High-resolution imaging; Image reconstruction; Irrigation; Microscopy; Osteoarthritis; Osteoporosis; Signal to noise ratio; Synchrotron radiation; Tomography; 3D image analysis; Bones; X-ray micro-tomography;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2009. ISBI '09. IEEE International Symposium on
Conference_Location :
Boston, MA
ISSN :
1945-7928
Print_ISBN :
978-1-4244-3931-7
Electronic_ISBN :
1945-7928
Type :
conf
DOI :
10.1109/ISBI.2009.5193119
Filename :
5193119
Link To Document :
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