• DocumentCode
    2805722
  • Title

    Markov Chain Inference From Microarray Data

  • Author

    Almeida, Ígor Lorenzato ; Pechmann, Denise Regina ; Luis, Alvaro

  • Author_Institution
    UNISINOS-PIPCA, Brazil
  • fYear
    2006
  • fDate
    Nov. 2006
  • Firstpage
    133
  • Lastpage
    141
  • Abstract
    Array technologies have made it straightforward to monitor simultaneously the expression pattern of thousands of genes. Thus, a lot of data is being generated and the challenge now is to discover how to extract useful information from these data sets. Microarray data is highly specialized, involves several variables in a non-linear and temporal way, demanding nonlinear recurrent free models, which are complex to formulate and to analyse in a simple way. Markov Chains are easily visualized in the form of graphs of states, which show the influences among the gene expression levels and their changes in time. In this work, we propose a new approach to microarray data analysis, by extracting a Markov Chain from Microarray Data. Two aspects are of interest for the researcher: the time evolution of the genic expression and their mutual influence in the form of regulatory networks.
  • Keywords
    Bioinformatics; Data analysis; Data mining; Data visualization; Databases; Gene expression; Genomics; Monitoring; Organisms; Recurrent neural networks;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Artificial Intelligence, 2006. MICAI '06. Fifth Mexican International Conference on
  • Conference_Location
    Mexico City, Mexico
  • Print_ISBN
    0-7695-2722-1
  • Type

    conf

  • DOI
    10.1109/MICAI.2006.29
  • Filename
    4022146