DocumentCode
2805722
Title
Markov Chain Inference From Microarray Data
Author
Almeida, Ígor Lorenzato ; Pechmann, Denise Regina ; Luis, Alvaro
Author_Institution
UNISINOS-PIPCA, Brazil
fYear
2006
fDate
Nov. 2006
Firstpage
133
Lastpage
141
Abstract
Array technologies have made it straightforward to monitor simultaneously the expression pattern of thousands of genes. Thus, a lot of data is being generated and the challenge now is to discover how to extract useful information from these data sets. Microarray data is highly specialized, involves several variables in a non-linear and temporal way, demanding nonlinear recurrent free models, which are complex to formulate and to analyse in a simple way. Markov Chains are easily visualized in the form of graphs of states, which show the influences among the gene expression levels and their changes in time. In this work, we propose a new approach to microarray data analysis, by extracting a Markov Chain from Microarray Data. Two aspects are of interest for the researcher: the time evolution of the genic expression and their mutual influence in the form of regulatory networks.
Keywords
Bioinformatics; Data analysis; Data mining; Data visualization; Databases; Gene expression; Genomics; Monitoring; Organisms; Recurrent neural networks;
fLanguage
English
Publisher
ieee
Conference_Titel
Artificial Intelligence, 2006. MICAI '06. Fifth Mexican International Conference on
Conference_Location
Mexico City, Mexico
Print_ISBN
0-7695-2722-1
Type
conf
DOI
10.1109/MICAI.2006.29
Filename
4022146
Link To Document