Title :
MRI-ultrasound registration for targeted prostate biopsy
Author :
Narayanan, R. ; Kurhanewicz, J. ; Shinohara, K. ; Crawford, E.D. ; Simoneau, A. ; Suri, J.S.
Author_Institution :
Eigen LLC, Grass Valley, CA, USA
fDate :
June 28 2009-July 1 2009
Abstract :
T2-weighted magnetic resonance images (MRI) imaging using an endorectal coil combined with a pelvic phased-array coil has been shown to provide high resolution images of the prostate. To integrate MRI analysis in standard prostate biopsy procedures, preoperative MRI must be accurately registered to 3-D transrectal ultrasound (TRUS) images. Shape changes due to patient motion, or drugs can induce further differences in glandular shape variation between preoperative MRI and 3-D TRUS during biopsy. In the proposed work, we model the deformation relating MRI and TRUS so as to enable analysis of MRI in conjunction with ultrasound (color blended or side-by-side) for planning of biopsy targets. Registration of MRI at various resolutions and endorectal balloon volumes and ultrasound volumes yielded average fiducial registration error of 3.06 mm using 6 and 12 bead phantoms.
Keywords :
biomedical MRI; biomedical ultrasonics; cancer; drugs; image registration; image resolution; medical image processing; phantoms; tumours; 3D transrectal ultrasound; MRI-ultrasound registration; T2-weighted magnetic resonance image; endorectal coil; fiducial registration error; glandular shape variation; high-resolution images; pelvic phased-array coil; prostate biopsy; Biopsy; Coils; High-resolution imaging; Image analysis; Image resolution; Magnetic analysis; Magnetic resonance; Magnetic resonance imaging; Shape; Ultrasonic imaging; MRI; biopsy; cancer; prostate; ultrasound;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2009. ISBI '09. IEEE International Symposium on
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-3931-7
Electronic_ISBN :
1945-7928
DOI :
10.1109/ISBI.2009.5193221