• DocumentCode
    2807810
  • Title

    Detection of Lung Cancer with Breath Biomarkers Based on SVM Regression

  • Author

    Ding, Siqi ; Hu, Tianlin ; Shen, Yang ; Lin, Chun ; Huang, Yuanqing

  • Author_Institution
    Dept. of Mech. & Electr. Eng., Xiamen Univ., Xiamen, China
  • Volume
    2
  • fYear
    2009
  • fDate
    14-16 Aug. 2009
  • Firstpage
    131
  • Lastpage
    138
  • Abstract
    According to feature extraction of high order cumulant, a new method of detecting lung cancer is proposed applying support vector machine model to recognize the mixed volatile organic compound (VOC) infrared spectrum, where the primary and secondary absorbed peaks are seriously overlapped. The number of spectrum channel of the original spectrum data is large; hence, the transmitted spectrogram is mapped to four-order cumulant space and detached from each firstly. In this simulation experiment, concentration of 19 VOCs was regressed by SVM and the result shows that the method performed well in identification. The average correct rate of component recognition is more than 95.5% when component concentration of VOC is not less than 1%. MSE and MAE were introduced to assess the performance of the method. Prediction adopting SVM and ANN is compared.
  • Keywords
    cancer; feature extraction; higher order statistics; infrared spectra; lung; medical diagnostic computing; medical signal processing; organic compounds; regression analysis; signal detection; spectroscopy computing; support vector machines; SVM regression; breath biomarkers; feature extraction; four-order cumulant space; lung cancer detection; mixed volatile organic compound infrared spectrum; spectrogram; spectrum channel; support vector machine model; Biomarkers; Cancer detection; Feature extraction; Gas detectors; Infrared detectors; Infrared spectra; Lungs; Spectrogram; Support vector machines; Volatile organic compounds; Feature extraction; High order cumulant; Support vector machine; Volatile organic compound;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Natural Computation, 2009. ICNC '09. Fifth International Conference on
  • Conference_Location
    Tianjin
  • Print_ISBN
    978-0-7695-3736-8
  • Type

    conf

  • DOI
    10.1109/ICNC.2009.557
  • Filename
    5362819