Title :
Image guided complex dose delivery for small animal radiotherapy
Author :
Matinfar, Mohammad ; Iyer, Santosh ; Ford, Eric ; Wong, John ; Kazanzides, Peter
Author_Institution :
Dept. of Comput. Sci., Johns Hopkins Univ., Baltimore, MD, USA
fDate :
June 28 2009-July 1 2009
Abstract :
The purpose of the small animal radiation research platform (SARRP) is to demonstrate computed tomography, conformal irradiation, and treatment planning capabilities for small animals. The SARRP is a portable system for precision irradiation with beam sizes down to approximately 0.5 mm and optimally planned radiation with on-board cone-beam CT (CBCT) guidance. This paper describes the utilization of the precision radiation beam on the SARRP for ldquodose paintingrdquo complex structures in the mouse brain. Pencil beam dose painting aims to target the tumor as accurately as possible and give it the highest dose of radiation while sparing normal tissue as much as possible.
Keywords :
brain; cancer; computerised tomography; diagnostic radiography; radiation therapy; tumours; CBCT; SARRP; cone-beam computed tomography; image guided complex dose delivery; mouse brain; pencil beam dose painting; radiotherapy; size 0.5 mm; small animal radiation research platform; Animals; Collimators; Computed tomography; Laboratories; Medical treatment; Neoplasms; Optical imaging; Painting; Robotic assembly; X-ray imaging; Computer assisted therapy; Image guided radiation; Small animal research;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2009. ISBI '09. IEEE International Symposium on
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-3931-7
Electronic_ISBN :
1945-7928
DOI :
10.1109/ISBI.2009.5193287
