Image guided complex dose delivery for small animal radiotherapy

Author

Matinfar, Mohammad ; Iyer, Santosh ; Ford, Eric ; Wong, John ; Kazanzides, Peter

Author_Institution

Dept. of Comput. Sci., Johns Hopkins Univ., Baltimore, MD, USA

fYear

2009

fDate

June 28 2009-July 1 2009

Firstpage

1243

Lastpage

1246

Abstract

The purpose of the small animal radiation research platform (SARRP) is to demonstrate computed tomography, conformal irradiation, and treatment planning capabilities for small animals. The SARRP is a portable system for precision irradiation with beam sizes down to approximately 0.5 mm and optimally planned radiation with on-board cone-beam CT (CBCT) guidance. This paper describes the utilization of the precision radiation beam on the SARRP for ldquodose paintingrdquo complex structures in the mouse brain. Pencil beam dose painting aims to target the tumor as accurately as possible and give it the highest dose of radiation while sparing normal tissue as much as possible.

Keywords

brain; cancer; computerised tomography; diagnostic radiography; radiation therapy; tumours; CBCT; SARRP; cone-beam computed tomography; image guided complex dose delivery; mouse brain; pencil beam dose painting; radiotherapy; size 0.5 mm; small animal radiation research platform; Animals; Collimators; Computed tomography; Laboratories; Medical treatment; Neoplasms; Optical imaging; Painting; Robotic assembly; X-ray imaging; Computer assisted therapy; Image guided radiation; Small animal research;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Imaging: From Nano to Macro, 2009. ISBI '09. IEEE International Symposium on

Conference_Location

Boston, MA

ISSN

1945-7928

Print_ISBN

978-1-4244-3931-7

Electronic_ISBN

1945-7928

Type

conf

DOI

10.1109/ISBI.2009.5193287

Filename

5193287