Title :
Microscopic Image Analysis and Recognition On Pathological Cells
Author :
Liu, Boqiang ; Yin, Cong ; Liu, Zhongguo ; Zhang, Zhenwang ; Gao, Junbo ; Zhu, Minghui ; Gu, Jason ; Xu, Kai
Author_Institution :
Shandong Univ., Jinan
Abstract :
According to the features of the configuration and color information on the cancer cells, an adaptive automatic threshold segmentation based on the RGB and HIS color spaces is presented, which is available to segment suspected cancer cells and nucleus from the complex backgrounds in the microscopic images. The edges of the suspected cancer cells and nucleus are detected by using Canny operator. Using the technology of eight-chain code tracking, the feature values of suspected cancer cells are extracted. The feature values consists of the perimeter, the area, the height, the width, the circularity, the rectangularity, the extension and the area ratio between the nucleus and the cytolympth. Based on feature values, a two-round recognition scheme combined with morphologic and colourometry is proposed to recognize and classify the pathological and normal cells. The results show that the proposed algorithm can efficiently segment cell images and receive higher accuracy of cancer cell diagnosis.
Keywords :
biomedical optical imaging; cancer; cellular biophysics; edge detection; feature extraction; image classification; image colour analysis; image motion analysis; image segmentation; medical image processing; optical microscopy; Canny operator; HIS color space; RGB color space; adaptive automatic threshold segmentation; cancer cell diagnosis; edge detection; eight-chain code tracking; feature extraction; image classification; image recognition; microscopic image analysis; pathological cell; Cancer detection; Feature extraction; Image analysis; Image color analysis; Image edge detection; Image recognition; Image segmentation; Microscopy; Pathology; Space technology;
Conference_Titel :
Electrical and Computer Engineering, 2007. CCECE 2007. Canadian Conference on
Conference_Location :
Vancouver, BC
Print_ISBN :
1-4244-1020-7
Electronic_ISBN :
0840-7789
DOI :
10.1109/CCECE.2007.261