Title :
Design of an ROC study using simulated lesions in whole-body FDG-PET
Author_Institution :
Mallinckrodt Inst. of Radiol., St. Louis, MO, USA
Abstract :
The authors propose to use ROC criteria to compare the effect on lesion detectability of OSEM reconstruction, compared with conventional FBP, and the effect of segmented attenuation correction (S-A/C) on lesion detectability in whole-body FDG-PET. This work includes the development of techniques to insert simulated lesions into patient images in a realistic fashion, obviating the need to an intuitive extrapolation from phantom-based results to the clinical setting. The authors explore the issues involved in designing such a study
Keywords :
image reconstruction; image segmentation; medical image processing; positron emission tomography; F; OSEM reconstruction; ROC study design; conventional FBP; intuitive extrapolation; medical diagnostic imaging; nuclear medicine; segmented attenuation correction; simulated lesions; whole-body FDG-PET; Attenuation; Extrapolation; Image segmentation; Lesions; Medical simulation; Nuclear measurements; Nuclear medicine; Performance evaluation; Radiology; Signal processing;
Conference_Titel :
Nuclear Science Symposium, 1997. IEEE
Conference_Location :
Albuquerque, NM
Print_ISBN :
0-7803-4258-5
DOI :
10.1109/NSSMIC.1997.670594
