DocumentCode :
2829172
Title :
3D microscopic imaging by synchrotron radiation micro/nano-CT
Author :
Peyrin, Françoise ; Pacureanu, Alexandra ; Langer, Max
fYear :
2011
fDate :
11-14 Sept. 2011
Firstpage :
3057
Lastpage :
3060
Abstract :
Biological microscopic imaging is receiving increasing interest with the development of new modalities. In this context Synchrotron Radiation (SR) Nano-CT demonstrates a high potential in opening new horizons. We recall the principle of SR micro-CT and its advantages over standard X-ray micro-CT in terms of accuracy and signal to noise ratio. We briefly present data acquisition and reconstruction in absorption and phase CT. While in the first case image reconstruction is based simply on the standard filtered back projection algorithm, in the later case it involves a preliminary step of phase retrieval. Applications of this technique in bone research in conjunction with specific image analysis developments are shown. At the micrometer scale, trabecular and cortical bone have been analyzed in human samples and mice. At the nanometer scale, we present recent data on the osteocyte network which has never before been investigated in 3D. Open problems for the segmentation and quantification of the complex canalicular network are highlighted.
Keywords :
biomedical imaging; computerised tomography; data acquisition; image reconstruction; synchrotron radiation; 3D microscopic imaging; biological microscopic imaging; data acquisition; image reconstruction; phase retrieval; synchrotron radiation micro/nano-CT; Bones; Computed tomography; Irrigation; Nanobioscience; Strontium; Three dimensional displays; X-ray CT; bone micro-architecture; micro-CT; nano-CT; osteocyte network; synchrotron radiation;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Image Processing (ICIP), 2011 18th IEEE International Conference on
Conference_Location :
Brussels
ISSN :
1522-4880
Print_ISBN :
978-1-4577-1304-0
Electronic_ISBN :
1522-4880
Type :
conf
DOI :
10.1109/ICIP.2011.6116309
Filename :
6116309
Link To Document :
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