LCG-MRF-Based Segmentation of MRI Brain Images

Segmentation of MRI brain images plays a critical role in medical image processing and analysis. In this paper, a new method based on Markov Random Field (MRF) is proposed for segmentation of MR brain images. We consider the low-level MRF as a linear combination of Gaussians (LCG) with positive and negative component, and we use the modified Expectation-maximization (MEM) algorithm to estimate the mean, variance and proportion for each distribution.The MEM algorithm is sensitive to initial parameters, so we improve the method of initialization. In high-level MRF, we use Potts model to describe the label image. By using the Bayesian maximum a posterior (MAP) rule, the segmentation problem is converted to precisely identify the models parameters. The MAP estimation is obtained using the Metroplis algorithm to search the optimization. The experimental results show that the proposed method is effective for segmentation of MR brain images.