Title :
Leukocyte´s nucleus segmentation using active contour in YCbCr colour space
Author :
Sadr, Ali ; Jahed, Mehran ; Salehian, Pirooz ; Eslami, Abouzar
Author_Institution :
Sharif Univ. of Technol., Tehran, Iran
fDate :
Nov. 30 2010-Dec. 2 2010
Abstract :
Blood cell segmentation is a crucial part of many medical and laboratory procedures such as cell counting and blood cell disorder diagnosis. Among different types of blood cells, white blood cells are the most important clinically, as they suffer greatest from blood disorders. In this paper we propose a method for automatic segmentation of white blood cells nucleus. A distinctive function is used in YCbCr color space to segment the white blood cells nucleus. Next, the sub-images are extracted which contain the whole body of white blood cell nucleus. Then an active contour method is applied to the sub-images extracted from the previous step to accurately segment the cell nucleus boundary. Our analysis conducted on 20 samples, show a great success on segmentation of white blood cells nucleus.
Keywords :
biomedical optical imaging; blood; cellular biophysics; image colour analysis; image segmentation; medical image processing; YCbCr colour space; active contour; blood cell disorder diagnosis; blood cell segmentation; cell counting; leukocyte; nucleus segmentation; subimages extraction; white blood cells; Algorithm design and analysis; Biomedical imaging; Filtering; Image color analysis; Image edge detection; Image segmentation; World Wide Web; Active Contour; Image segmentation; White blood cell nucleus; YCbCr colour space;
Conference_Titel :
Biomedical Engineering and Sciences (IECBES), 2010 IEEE EMBS Conference on
Conference_Location :
Kuala Lumpur
Print_ISBN :
978-1-4244-7599-5
DOI :
10.1109/IECBES.2010.5742239