DocumentCode
2845036
Title
Geiger photodiodes for diffuse optical correlation tomography
Author
Sia, R. ; Stapels, C.J. ; Johnson, E.B. ; Durduran, T. ; Zhou, C. ; Yu, G. ; Yodh, A.G. ; Augustine, F.L. ; Christian, J.F.
Author_Institution
Radiat. Monitoring Devices, Watertown
Volume
6
fYear
2007
fDate
Oct. 26 2007-Nov. 3 2007
Firstpage
4062
Lastpage
4067
Abstract
Based on CMOS Geiger photodiode (GPD) pixels developed at RMD Inc. and fabricated with MOSIS consortium, we present a detector design that is capable of providing highspeed and single optical photon sensitivity in the near infrared region. The integration of the electronic reset with these CMOS pixels enables their use in a cost-effective large imaging array to provide a substantial increase in the signal-to-noise ratio and facilitate the high-speed, pixel-level signal processing required for photon-counting Diffuse Correlation Tomography (DCT). DCT is an imaging technique in progress that promises to provide a method for routine, non-invasive cancer screening and treatment by imaging blood flow, tissue oxygenation, and the distinct vasculature associated with the angiogenesis of cancerous growth using non-ionizing radiation. In this work, we present results of the design, fabrication and characterization of the CMOS Geiger pixels and their associated integrated reset circuits for DCT measurements.
Keywords
CMOS image sensors; biomedical optical imaging; cancer; haemodynamics; optical tomography; photodiodes; tumours; CMOS Geiger photodiode; angiogenesis; blood flow; cancer screening; diffuse optical correlation tomography; high-speed pixel-level signal processing; signal-to-noise ratio; tissue oxygenation; Discrete cosine transforms; High speed optical techniques; Infrared detectors; Optical design; Optical imaging; Optical sensors; Optical signal processing; Photodiodes; Pixel; Tomography;
fLanguage
English
Publisher
ieee
Conference_Titel
Nuclear Science Symposium Conference Record, 2007. NSS '07. IEEE
Conference_Location
Honolulu, HI
ISSN
1095-7863
Print_ISBN
978-1-4244-0922-8
Electronic_ISBN
1095-7863
Type
conf
DOI
10.1109/NSSMIC.2007.4437020
Filename
4437020
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