Title :
Flexible Silicon Microneedles Array for Micro Fluid Transfer
Author :
Bin Ma ; Gan, Zhiyin ; Liu, Sheng
Author_Institution :
Inst. of Microsystems, Huazhong Sci. & Technol. Univ., Wuhan
Abstract :
This paper reports on a new method of using silicon micro needle in bio-medical application. The hollow micro needle array have been designed and fabricated from single crystal silicon for transdermal delivery. The machined micro needles are shank height of 150mum with 250mum center-to-center spacing. The needle size, density and shape are controlled by independent processing steps. Packaging technology incorporates a micro needles array affixed to a polymeric adhesive base. The maximal adhesive patch size is 2 cm2. Flow rate test is proved that the polymeric base construction is important to function of micro needles array. Glucose solution tests show that surface tension is the dominant force to affect the characters of flow in micro needles channel
Keywords :
drug delivery systems; microchannel flow; packaging; 150 micron; 250 micron; bio-medical application; drug delivery; flow rate test; glucose solution tests; micro fluid transfer; micro needle channel; polymeric adhesive; polymeric base construction; silicon microneedle array; transdermal delivery; Needles; Packaging machines; Polymers; Process control; Shape control; Silicon; Size control; Sugar; Surface tension; Testing; Bio-Medical application; drug delivery; micro needles array; packaging; transdermal;
Conference_Titel :
Electronic Packaging Technology, 2005 6th International Conference on
Conference_Location :
Shenzhen
Print_ISBN :
0-7803-9449-6
DOI :
10.1109/ICEPT.2005.1564615