Title :
Anatomy-based dose optimization for HDR-brachytherapy of the prostate using fast simulated annealing algorithm
Author :
Lessard, Etienne ; Pouliot, Jean
Abstract :
The goal of this work is to correctly and completely take into account the anatomical information in the treatment planning of prostate cancer for high dose rate brachytherapy. By using fast simulated annealing algorithm to govern an inverse planning optimization, a highly conformal dose coverage to the target volume is obtained while minimizing urinary and rectal morbidity. Preliminary results show that the authors´ fast simulated annealing algorithm can obtain a highly conformal dose to the prostate while preserving urethra and rectum wall within 15 to 20 minutes of cpu time
Keywords :
biological organs; dosimetry; radiation therapy; simulated annealing; 15 to 20 min; HDR-brachytherapy; anatomical information; anatomy-based dose optimization; cpu time; fast simulated annealing algorithm; high dose rate brachytherapy; highly conformal dose coverage; inverse planning; prostate cancer treatment planning; rectal morbidity; rectum wall preservation; target volume; therapeutic nuclear medicine; urethra preservation; urinary morbidity; Anatomy; Applicators; Biomedical applications of radiation; Brachytherapy; Catheters; Implants; Intensity modulation; Prostate cancer; Shape; Simulated annealing;
Conference_Titel :
Engineering in Medicine and Biology Society, 2000. Proceedings of the 22nd Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
Print_ISBN :
0-7803-6465-1
DOI :
10.1109/IEMBS.2000.901437
