Understanding the Collective Coulomb Forces of the ions in the microfluidic channel

We utilized rapid prototyping technology to fabricate the resin substrate with a PMMA cover slide as close-ended chip to avoid evaporation. And we applied AC voltages in ionic solution to improve the S/N ratio. By measuring ionic phase during frequency shift, we acquired data in a complex form, that is, real and imaginary part of currents. The measuring system implemented in lock-in amplifier which can realize high-sensitivity. Base on this concept, we demand to develop a novel two-dimensional database of molecular detection in the future.