Silk-carbon nanotube composite for stem cell neuronal differentiation

Author

Chen, Chi-Shuo ; Le, Catherine ; Soni, Sushant ; Chen, Eric Y-T ; Chin, Wei-Chun

Author_Institution

Bioeng., Univ. of California, Merced, Merced, CA, USA

fYear

2011

fDate

21-24 June 2011

Firstpage

1

Lastpage

2

Abstract

This study aims to create a new paradigm for building 3D silk-carbon nanotube (CNT) based composite scaffolds in order to acquire better neuron differentiation efficiency from human embryonic stem cells (hESCs). CNT and silk have been successfully used for neuronal differentiation and tissue engineering applications. The silk-CNT composite scaffolds can serve as efficient support matrices for stem cell derived neuronal transplants that offer a promising opportunity for nerve injury treatments in spinal cord injury (SCI) patients.

Keywords

biomedical materials; carbon nanotubes; cellular biophysics; nanocomposites; nanomedicine; neurophysiology; tissue engineering; 3D silk-carbon nanotube composite; C; composite scaffold; human embryonic stem cells; nerve injury treatment; neuron differentiation efficiency; spinal cord injury; stem cell neuronal differentiation; tissue engineering; Fluorescence; Humans; Nerve fibers; Stem cells; Substrates; Tissue engineering; carbon nanotube; neuron and differentiation; silk; stem cell;

fLanguage

English

Publisher

ieee

Conference_Titel

Nanoelectronics Conference (INEC), 2011 IEEE 4th International

Conference_Location

Tao-Yuan

ISSN

2159-3523

Print_ISBN

978-1-4577-0379-9

Electronic_ISBN

2159-3523

Type

conf

DOI

10.1109/INEC.2011.5991795

Filename

5991795