Title :
Ex vivo and in vivo oral cancer diagnosis using backward-collected third harmonic generation biopsy
Author :
Tai, Shih-Peng ; Shieh, Dar-Bin ; Lee, Wen-Jeng ; Yu, Che-Hang ; Wu, Ping-Ching ; Wu, Yana ; Sun, Chi-Kuang
Author_Institution :
Dept. of Electr. Eng., Nat. Taiwan Univ., Taipei
Abstract :
Ex vivo and in vivo oral cancer diagnoses are demonstrated using noninvasive third-harmonic-generation biopsy. Through its superior spatial resolution on nucleus, oral cancer cells in hamster oral cavities are successfully identified without any exogenous markers.
Keywords :
biomedical optical imaging; cancer; cellular biophysics; image resolution; optical harmonic generation; tumours; backward-collected third harmonic generation biopsy; cell nucleus; ex vivo oral cancer diagnosis; hamster oral cavities; in vivo oral cancer diagnosis; noninvasive diagnosis; oral cancer cells; spatial resolution; Biomedical optical imaging; Biopsy; Cancer; Fluorescence; Frequency conversion; In vivo; Nonlinear optics; Optical harmonic generation; Optical microscopy; Ultrafast optics; (180.6900) Three-dimensional microscopy; (190.4160) Mutiharmonic generation;
Conference_Titel :
Lasers and Electro-Optics, 2006 and 2006 Quantum Electronics and Laser Science Conference. CLEO/QELS 2006. Conference on
Conference_Location :
Long Beach, CA
Print_ISBN :
978-1-55752-813-1
Electronic_ISBN :
978-1-55752-813-1
DOI :
10.1109/CLEO.2006.4628199
