Title :
Generating controllable microbubbles inside individual cells using femtosecond laser pulses
Author :
Ye, Jing Yong ; Tse, Christine ; Zohdy, Marwa J. ; Hollman, Kyle ; Balogh, Lajos ; Norris, Theodore B. ; Donnel, Matthew O.
Author_Institution :
Center for Ultrafast Opt. Sci., Univ. of Michigan, Ann Arbor, MI
Abstract :
We demonstrate that microbubbles generated through optical breakdown in tissue phantoms or individual cells are controllable with laser parameters. The controlled microbubbles can be used as an acoustically detectable agent for diagnostic and therapeutic applications.
Keywords :
bio-optics; biological tissues; biomedical ultrasonics; bubbles; cellular biophysics; electric breakdown; high-speed optical techniques; laser applications in medicine; patient treatment; phantoms; acoustically detectable agent; diagnostic applications; femtosecond laser pulses; individual cells; microbubbles; optical breakdown; therapeutic applications; tissue phantoms; Acoustic pulses; Acoustic signal detection; Biomedical optical imaging; Electric breakdown; Focusing; Laser tuning; Optical control; Optical pulse generation; Optical pulses; Ultrafast optics; (170.1020) Ablation of tissue; (170.7160) Ultrafast technology; (170.7180) Ultrasound diagnostics;
Conference_Titel :
Lasers and Electro-Optics, 2006 and 2006 Quantum Electronics and Laser Science Conference. CLEO/QELS 2006. Conference on
Conference_Location :
Long Beach, CA
Print_ISBN :
978-1-55752-813-1
Electronic_ISBN :
978-1-55752-813-1
DOI :
10.1109/CLEO.2006.4628302
