Generating controllable microbubbles inside individual cells using femtosecond laser pulses

Author

Ye, Jing Yong ; Tse, Christine ; Zohdy, Marwa J. ; Hollman, Kyle ; Balogh, Lajos ; Norris, Theodore B. ; Donnel, Matthew O.

Author_Institution

Center for Ultrafast Opt. Sci., Univ. of Michigan, Ann Arbor, MI

fYear

2006

fDate

21-26 May 2006

Firstpage

1

Lastpage

2

Abstract

We demonstrate that microbubbles generated through optical breakdown in tissue phantoms or individual cells are controllable with laser parameters. The controlled microbubbles can be used as an acoustically detectable agent for diagnostic and therapeutic applications.

Keywords

bio-optics; biological tissues; biomedical ultrasonics; bubbles; cellular biophysics; electric breakdown; high-speed optical techniques; laser applications in medicine; patient treatment; phantoms; acoustically detectable agent; diagnostic applications; femtosecond laser pulses; individual cells; microbubbles; optical breakdown; therapeutic applications; tissue phantoms; Acoustic pulses; Acoustic signal detection; Biomedical optical imaging; Electric breakdown; Focusing; Laser tuning; Optical control; Optical pulse generation; Optical pulses; Ultrafast optics; (170.1020) Ablation of tissue; (170.7160) Ultrafast technology; (170.7180) Ultrasound diagnostics;

fLanguage

English

Publisher

ieee

Conference_Titel

Lasers and Electro-Optics, 2006 and 2006 Quantum Electronics and Laser Science Conference. CLEO/QELS 2006. Conference on

Conference_Location

Long Beach, CA

Print_ISBN

978-1-55752-813-1

Electronic_ISBN

978-1-55752-813-1

Type

conf

DOI

10.1109/CLEO.2006.4628302

Filename

4628302