Title :
An Isochore Map of the Human Genome Based on the GCDT Method
Author :
Wang, Anhui ; Chang, Guiran ; Deng, Xuegong ; Zhao, Xingbo
Author_Institution :
Sch. of Inf. Sci. & Eng., Northeastern Univ., Shenyang, China
Abstract :
Due to the isochore structures associate with many important biological functions, a good segment algorithm for the isochore boundaries will provide much insight into the understanding of the human genome. The isochore map of human genome has been obtained by an algorithm based on the technique of GCDT in this paper. The obtained boundaries match well with the GCDT images in visualization. The human genome has very clear isochore structures.
Keywords :
biology computing; data visualisation; genomics; GCDT method; human genome; isochore map; Animal structures; Bioinformatics; Biological cells; Genomics; Humans; Information processing; Laboratories; Partitioning algorithms; Sequences; Visualization; GC content; GCDT; chromosome; isochore;
Conference_Titel :
Information Processing, 2009. APCIP 2009. Asia-Pacific Conference on
Conference_Location :
Shenzhen
Print_ISBN :
978-0-7695-3699-6
DOI :
10.1109/APCIP.2009.225
