Title :
Fiber optic evanescent wave biosensor for biomolecular detection
Author :
Yu, Sheng-Hong ; Chen, Cheng-Hau ; Chiang, Huihua Kenny
Author_Institution :
Inst. of Biomed. Eng., Nat. Yang-Ming Univ., Taipei, Taiwan
Abstract :
An evanescent wave fluorescence-based fiber-optic biosensor is developed for high sensitivity, low cost, compact design and real-time in-situ monitoring. In the research, we accomplished the fiber-optical biosensor system to monitor the reaction of IgG-Anti rabbit IgG and Biotin-Streptavidin, and the kinetic association and dissociation constant of target analytes were calculated.
Keywords :
biochemistry; biosensors; fibre optic sensors; fluorescence; molecular biophysics; Biotin-Streptavidin reaction monitoring; IgG-Anti rabbit IgG reaction monitoring; biomolecular detection; evanescent wave fluorescence biosensor; fiber-optical biosensor system; kinetic association; kinetic dissociation constant; target analytes; Biomedical engineering; Biomedical monitoring; Biosensors; Fluorescence; Immune system; Kinetic theory; Optical fiber sensors; Optical fibers; Rabbits; Time factors;
Conference_Titel :
Biophotonics, 2004. APBP 2004. The Second Asian and Pacific Rim Symposium on
Print_ISBN :
0-7803-8676-0
DOI :
10.1109/APBP.2004.1412333
