• DocumentCode
    288828
  • Title

    Backpropagation learning on ribosomal binding sites in DNA sequences using preprocessed features

  • Author

    Pratt, Lorien Y. ; Tracy, Lauren L. ; Noordewier, Michiel

  • Author_Institution
    Dept. of Math. & Comput. Sci., Colorado Sch. of Mines, Golden, CO, USA
  • Volume
    5
  • fYear
    1994
  • fDate
    27 Jun-2 Jul 1994
  • Firstpage
    3332
  • Abstract
    Several studies have explored how neural networks can be used to find genes within regions of previously uncharacterized deoxyribonucleic acid (DNA). This paper describes the creation of a neural network training set for determining which part of a DNA strand codes for an important genetic feature called a ribosomal binding site (RBS). Based on previous research on detecting other genetic features, this data set contains preprocessed features that reflect biologically meaningful patterns in the raw base pair [ACTG]* language. We also describe preliminary empirical results indicating neural network performance that is superior to all other automated methods for detecting RBS´s
  • Keywords
    DNA; biology computing; feature extraction; genetics; learning (artificial intelligence); neural nets; pattern classification; DNA sequences; RBS extraction; backpropagation learning; genetic feature; neural networks; ribosomal binding sites; strand codes; Backpropagation; Biological information theory; Cells (biology); DNA; Genetics; Laboratories; Neural networks; Organisms; Proteins; Sequences;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Neural Networks, 1994. IEEE World Congress on Computational Intelligence., 1994 IEEE International Conference on
  • Conference_Location
    Orlando, FL
  • Print_ISBN
    0-7803-1901-X
  • Type

    conf

  • DOI
    10.1109/ICNN.1994.374790
  • Filename
    374790