DocumentCode
288828
Title
Backpropagation learning on ribosomal binding sites in DNA sequences using preprocessed features
Author
Pratt, Lorien Y. ; Tracy, Lauren L. ; Noordewier, Michiel
Author_Institution
Dept. of Math. & Comput. Sci., Colorado Sch. of Mines, Golden, CO, USA
Volume
5
fYear
1994
fDate
27 Jun-2 Jul 1994
Firstpage
3332
Abstract
Several studies have explored how neural networks can be used to find genes within regions of previously uncharacterized deoxyribonucleic acid (DNA). This paper describes the creation of a neural network training set for determining which part of a DNA strand codes for an important genetic feature called a ribosomal binding site (RBS). Based on previous research on detecting other genetic features, this data set contains preprocessed features that reflect biologically meaningful patterns in the raw base pair [ACTG]* language. We also describe preliminary empirical results indicating neural network performance that is superior to all other automated methods for detecting RBS´s
Keywords
DNA; biology computing; feature extraction; genetics; learning (artificial intelligence); neural nets; pattern classification; DNA sequences; RBS extraction; backpropagation learning; genetic feature; neural networks; ribosomal binding sites; strand codes; Backpropagation; Biological information theory; Cells (biology); DNA; Genetics; Laboratories; Neural networks; Organisms; Proteins; Sequences;
fLanguage
English
Publisher
ieee
Conference_Titel
Neural Networks, 1994. IEEE World Congress on Computational Intelligence., 1994 IEEE International Conference on
Conference_Location
Orlando, FL
Print_ISBN
0-7803-1901-X
Type
conf
DOI
10.1109/ICNN.1994.374790
Filename
374790
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