Title :
Modeling and simulation of piezoelectric based micro cantilever systems for Prostate Specific Antigen
Author :
Gupta, Raghav ; Swaminathan, Sundaram
Author_Institution :
Dept. of Electr. & Electron. Eng., BITS Pilani, Dubai, United Arab Emirates
Abstract :
This work proposes a novel compact piezoelectric (PZT) microcantilever transducer model using COMSOL Multiphysics for detection of Prostate Cancer. Prostate Specific Antigen (PSA) level detection is done via Transport of Diluted Species and Laminar flow physics module. Reaction between PSA Antigen and its protein Antibody takes place on cantilever surface, which influence the mechanical displacement and the piezo voltage. Analysis of the model indicate high sensitivity in the PZT voltage for changes in PSA concentration.
Keywords :
bioMEMS; biochemistry; biological organs; biomedical measurement; biomedical transducers; biosensors; cancer; cantilevers; electrochemical sensors; finite element analysis; laminar flow; medical computing; microfluidics; molecular biophysics; piezoelectric transducers; proteins; COMSOL Multiphysics; PSA antigen-protein antibody reaction; PSA concentration change sensitivity; PSA level detection; PZT microcantilever transducer model; PZT voltage sensitivity; compact piezoelectric microcantilever transducer model; diluted species transport; laminar flow physics module; mechanical displacement; piezo voltage; piezoelectric based microcantilever system; prostate cancer detection; prostate specific antigen; simulation; Biosensors; Mathematical model; Plasmas; Prostate cancer; Proteins; Stress; Micro Cantilever; Piezo Electric; Prostate Specific Antigen(PSA);
Conference_Titel :
Next-Generation Electronics (ISNE), 2015 International Symposium on
Conference_Location :
Taipei
DOI :
10.1109/ISNE.2015.7131950
