Crosstalk resistant adaptive noise cancellation applied to somatosensory evoked potential enhancement

Somatosensory evoked potentials (SEPs) are extremely useful in peripheral nerve monitoring and in the diagnosis of various neuromuscular disorders. However, surface measurements of these potentials often result in imperceptible SEP waveforms due to the very poor signal-to-noise ratio (SNR). Adaptive noise cancelling is an attractive technique which can be used to improve this poor SNR. One of the important factors that affect the performance of an adaptive noise canceller (ANC) is the presence of SEP components in the reference channel of the ANC. The authors propose a novel multichannel crosstalk resistant adaptive noise canceller (MCRANC) for offsetting the problems caused by the “SEP” crosstalk. The performance of this MCRANC is evaluated analytically and through simulations