A hybrid stochastic/deterministic model of intracellular HIV infection dynamics and estimation of viral production parameters

This work is the initial step in development of an intracellular/extracellular model that describes the infection progression at the animal level, while having the required accuracy at the cellular level. Hence, a hybrid stochastic/deterministic intracellular model of HIV infection is developed to accurately model the events inside the infected cell. The model determines the probability of successful completion of intracellular infection cycle and estimates the number of produced virions per infected cell.