DocumentCode :
2903598
Title :
Mathematical model based on the Jeffreys type equation for description of gene expression
Author :
Gula, I.A. ; Samsonov, A.M.
Author_Institution :
Ioffe Phys. Tech. Inst., St. Petersburg, Russia
fYear :
2013
fDate :
27-31 May 2013
Firstpage :
72
Lastpage :
77
Abstract :
The classical diffusion model widely used for description of transport processes results, in general, in an infinite velocity of particles propagation. It is hardly applicable to the description of protein transport in biological systems, containing heavy molecules. In the 1950s the Jeffreys type equation was applied to govern the motion of rheological substances. Later, using this equation, the transport problem statement was modified to consider the gene expression in fruit fly embryo, and the model equation for protein concentration was proposed. The numerical solution of the coupled Jeffreys type equations with nonlinear terms is found for description of gap gene expression in early Drosophila embryo development and compared with the experimental data.
Keywords :
biochemistry; cellular transport; genetics; molecular biophysics; numerical analysis; physiological models; proteins; Drosophila embryo development; Jeffreys-type equation; biological systems; classical diffusion model; fruit fly embryo; gene expression; mathematical model; numerical solution; particle propagation; protein concentration; protein transport; rheological substances; transport processes; Biological system modeling; Data models; Embryo; Equations; Mathematical model; Numerical models; Proteins;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Days on Diffraction (DD), 2013
Conference_Location :
St. Petersburg
Print_ISBN :
978-1-4799-1037-3
Type :
conf
DOI :
10.1109/DD.2013.6712806
Filename :
6712806
Link To Document :
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