• DocumentCode
    2907493
  • Title

    DNA sequence analysis using fuzzy grammars

  • Author

    Molina-lozano, Herón ; Vallejo-Clemente, Edgar E. ; Morett-Sánchez, Juna E.

  • Author_Institution
    Interdiscipl. Prof. Unit of Eng. & Adv. Technol., Nat. Polytech. Inst., Mexico City
  • fYear
    2008
  • fDate
    1-6 June 2008
  • Firstpage
    1915
  • Lastpage
    1921
  • Abstract
    We propose to use fuzzy context-free grammars for the analysis of DNA sequences by using the Cocke-Younger-Kasami algorithm to estimate membership grades of a DNA sequence against the language of a fuzzy grammar. As a first example of the application of the proposed method we prove that is possible to determine a fuzzy grammar of a prototype DNA sequence and then found the membership grade of any arbitrary sequence against the specific pattern. As a second example, we formulate a fuzzy grammar from an alignment of promoters by a logo sequence of Escherichia Coli K12 then show how the proposed method can be used for the discovery of regulatory motifs.
  • Keywords
    biocomputing; fuzzy set theory; grammars; Cocke-Younger-Kasami algorithm; DNA sequence analysis; Escherichia Coli K12; fuzzy context-free grammars; fuzzy grammars; membership grades; regulatory motifs; DNA; Fuzzy systems; Sequences;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Fuzzy Systems, 2008. FUZZ-IEEE 2008. (IEEE World Congress on Computational Intelligence). IEEE International Conference on
  • Conference_Location
    Hong Kong
  • ISSN
    1098-7584
  • Print_ISBN
    978-1-4244-1818-3
  • Electronic_ISBN
    1098-7584
  • Type

    conf

  • DOI
    10.1109/FUZZY.2008.4630631
  • Filename
    4630631