Title :
Cell manipulation in microsystems for clinical and biological applications
Author :
Toner, Mehmet ; Irimia, Daniel
Author_Institution :
Harvard-Massachusetts Inst. of Technol., Boston
Abstract :
The mission of the center is to develop and promote living-cell-based microdevices as key technologies in medicine and biological sciences. By integrating engineering methods and biological research into novel microsystem technologies, we aim to provide unique capabilities to biomedical investigators to probe, manipulate, engineer, and analyze biological cells for diagnostic, prognostic and therapeutic advances and basic biology discovery. This brief review describes our recent work in microchips for blood analysis, microfabricated living cell arrays, and microfluidic gradient generators for studies of cellular chemotaxis.
Keywords :
bioMEMS; biological techniques; blood; cell motility; microfluidics; biological applications; blood analysis; cell manipulation; cellular chemotaxis; clinical applications; living-cell-based microdevices; microchips; microfabricated living cell arrays; microfluidic gradient generators; microsystems; Biomedical engineering; Cells (biology); Data mining; Engineering in medicine and biology; Hospitals; Medical diagnostic imaging; Microfluidics; Optical arrays; Sorting; White blood cells;
Conference_Titel :
Micro Electro Mechanical Systems, 2008. MEMS 2008. IEEE 21st International Conference on
Conference_Location :
Tucson, AZ
Print_ISBN :
978-1-4244-1792-6
Electronic_ISBN :
1084-6999
DOI :
10.1109/MEMSYS.2008.4443591
