Cell manipulation in microsystems for clinical and biological applications

Author

Toner, Mehmet ; Irimia, Daniel

Author_Institution

Harvard-Massachusetts Inst. of Technol., Boston

fYear

2008

fDate

13-17 Jan. 2008

Firstpage

54

Lastpage

57

Abstract

The mission of the center is to develop and promote living-cell-based microdevices as key technologies in medicine and biological sciences. By integrating engineering methods and biological research into novel microsystem technologies, we aim to provide unique capabilities to biomedical investigators to probe, manipulate, engineer, and analyze biological cells for diagnostic, prognostic and therapeutic advances and basic biology discovery. This brief review describes our recent work in microchips for blood analysis, microfabricated living cell arrays, and microfluidic gradient generators for studies of cellular chemotaxis.

Keywords

bioMEMS; biological techniques; blood; cell motility; microfluidics; biological applications; blood analysis; cell manipulation; cellular chemotaxis; clinical applications; living-cell-based microdevices; microchips; microfabricated living cell arrays; microfluidic gradient generators; microsystems; Biomedical engineering; Cells (biology); Data mining; Engineering in medicine and biology; Hospitals; Medical diagnostic imaging; Microfluidics; Optical arrays; Sorting; White blood cells;

fLanguage

English

Publisher

ieee

Conference_Titel

Micro Electro Mechanical Systems, 2008. MEMS 2008. IEEE 21st International Conference on

Conference_Location

Tucson, AZ

ISSN

1084-6999

Print_ISBN

978-1-4244-1792-6

Electronic_ISBN

1084-6999

Type

conf

DOI

10.1109/MEMSYS.2008.4443591

Filename

4443591