Title :
Evolving scale-free topologies using a Gene Regulatory Network model
Author :
Nicolau, Miguel ; Schoenauer, Marc
Author_Institution :
INRIA Saclay, Univ. Paris Sud, Orsay
Abstract :
A novel approach to generating scale-free network topologies is introduced, based on an existing artificial Gene Regulatory Network model. From this model, different interaction networks can be extracted, based on an activation threshold. By using an Evolutionary Computation approach, the model is allowed to evolve, in order to reach specific network statistical measures. The results obtained show that, when the model uses a duplication and divergence initialisation, such as seen in nature, the resulting regulation networks not only are closer in topology to scale-free networks, but also exhibit a much higher potential for evolution.
Keywords :
complex networks; evolutionary computation; topology; activation threshold; artificial gene regulatory network model; divergence initialisation; duplication; evolutionary computation approach; network statistical measures; scale-free topologies; Bioinformatics; Biological system modeling; Computational modeling; Evolution (biology); Evolutionary computation; Genomics; Network topology; Power generation; Proteins; Wiring;
Conference_Titel :
Evolutionary Computation, 2008. CEC 2008. (IEEE World Congress on Computational Intelligence). IEEE Congress on
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4244-1822-0
Electronic_ISBN :
978-1-4244-1823-7
DOI :
10.1109/CEC.2008.4631305