A Biomechanical model of spiculated tumours under mammographic compressions

Author

Wessel, Carolina ; Schnabel, Julia A. ; Brady, Sir Michael

Author_Institution

Dept. of Eng. Sci., Univ. of Oxford, Oxford, UK

fYear

2010

fDate

Aug. 31 2010-Sept. 4 2010

Firstpage

712

Lastpage

715

Abstract

The aim of this paper is to introduce effects well known to clinicians -but neglected to date- in the biomechanical modelling of breast malignant tumours. We develop a model of an isolated stellate breast tumour under mammographic compression forces. We study a range of reported mechanical properties, both linear elastic and hyperelastic. We also introduce different volumes of increased density/stiffness around the tumour. We show that each of these issues has a non-negligible effect on stresses and strains/deformations.

Keywords

biological organs; biomechanics; cancer; data compression; elastic deformation; image coding; mammography; medical image processing; tumours; biomechanical model; breast malignant tumours; deformations; density; hyperelastic properties; isolated stellate breast tumour; linear elastic properties; mammographic compressions; spiculated tumours; stiffness; strains; Breast tissue; Materials; Mathematical model; Strain; Stress; Tumors; Artifacts; Breast Neoplasms; Compressive Strength; Computer Simulation; Elastic Modulus; Female; Humans; Models, Biological; Radiographic Image Enhancement; Radiographic Image Interpretation, Computer-Assisted; Reproducibility of Results; Sensitivity and Specificity;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE

Conference_Location

Buenos Aires

ISSN

1557-170X

Print_ISBN

978-1-4244-4123-5

Type

conf

DOI

10.1109/IEMBS.2010.5626107

Filename

5626107