Title :
Gene delivery to skin with laser-induced stress wave
Author :
Ogura, Makoto ; Sato, Shunichi ; Terakawa, Mitsuhiro ; Ashida, Hiroshi ; Obara, Minoru
Author_Institution :
Keio University, Japan; makogura@obara.elec.keio.ac.jp
Abstract :
We investigated gene delivery by laser-induced stress waves (LISWs) generated by irradiating a solid target with nanosecond laser pulses. Highly efficient and site-specific gene transfer has been achieved by applying a few pulses of LISWs.
Keywords :
Chemical lasers; DNA; Fluorescence; In vivo; Laser theory; Optical pulse generation; Optical pulses; Skin; Solid lasers; Stress;
Conference_Titel :
Lasers and Electro-Optics, 2005. CLEO/Pacific Rim 2005. Pacific Rim Conference on
Print_ISBN :
0-7803-9242-6
DOI :
10.1109/CLEOPR.2005.1569507